姓名：苏波
职称：教授、博导、我校“百名青年学科带头人”
研究方向：
1. 新配体的设计及过渡金属催化的新反应的发现
2. 具有重要生物活性的手性杂环的设计与合成
3. 手性药物和具有重要生物活性的天然产物的合成
通讯地址：天津市津南区同砚路38号5357cc拉斯维加斯 106
电子邮件：subo@nankai.edu.cn
欢迎加入：本课题组欢迎“申请-考核制博士”、统考和推免硕士研究生、优秀的博士后和研究助理加入，请直接联系 subo@nankai.edu.cn
教师简介：
苏波教授本科毕业于郑州大学化学基地班，然后在我校元素有机国家重点实验室汪清民教授课题组取得博士学位。随后分别师从北京大学施章杰教授（973首席科学家）和美国加州大学伯克利分校John Hartwig教授(Wolf奖获得者、美国科学院院士)从事博士后研究，并于2020年5月加入5357cc拉斯维加斯和药物化学生物学国家重点实验室开展独立研究。
苏波教授研究涉及不对称有机合成、新配体的设计和新反应的发现，具有重要生物活性的天然产物的合成和手性药物合成等，取得了一系列创新性成果。截至目前发表论文30余篇，其中以第一作者(含并列一作)在Science (1篇)，Acc. Chem. Res. (1篇), J. Am. Chem. Soc. (4篇), Angew. Chem. Int. Ed. (3篇), Org. Lett., J. Agric. Food. Chem.等发表论文20篇，总引用次数1100余次。
代表性论文：
32. Su B*, Hartwig J*, Development of Chiral Ligands for the Transition Metal‐catalyzed Enantioselective Silylation and Borylation of C‐H Bonds Angew. Chem. Int. Ed. 2022, 61, 9, e202113343
31. Liu J, Su B*, Chen M*，Cu-Catalyzed Highly Stereoselective Syntheses of (E)-δ-Vinyl-homoallylic Alcohols Org. Lett. 2021, 23, 6035-6040
30. Oeschger R,1 Su B,1 Yu I, Ehinger C, Romero E, He S, Hartwig J, Science 2020, 368, 736-741 (1Equal contribution)
29. B Su, A Bunescu, Y Qiu, SJ Zuend, M Ernst, JF Hartwig. J. Am. Chem. Soc. 2020, 142, 7912-7919.
28. Y Xi,1 B Su,1 X Qi, S Pedram, P Liu, JF Hartwig J. Am. Chem. Soc. 2020, 142, 18213-18222 (1Equal contribution)
27. Su, B.;1 Lee T.;1 Hartwig, J. F., Ir-Catalyzed Intramolecular Silylation of C-H Bonds of Aliphatic Amines.
J. Am. Chem. Soc. 2018, 140, 18032. (1Equal contribution)
26. Su, B.; Hartwig, J. F., Ir-Catalyzed, Silyl-Directed, peri-Borylation of C-H Bonds in Fused Polycyclic Arenes and Heteroarenes Angew. Chem. Int. Ed. 2018, 57, 10163-10167.
25. Su, B.; Hartwig, J. F., Ir-Catalyzed Enantioselective, Intramolecular Silylation of Methyl C–H Bonds.
J. Am. Chem. Soc. 2017, 139, 12137-12140.
24. Su, B.; Zhou, T.-G.; Xu, P.-L.; Shi, Z.-J.; Hartwig, J. F., Enantioselective Borylation of Aromatic C−H Bonds with Chiral Dinitrogen Ligands. Angew. Chem. Int. Ed. 2017, 56, 7205-7208.
23. Su, B.; Zhou, T.G.; Li, X.W.; Shao, X.R.; Xu, P.L.; Wu, W.L.; Hartwig, J. F.; Shi Z.-J., A Chiral Nitrogen Ligand for Enantioselective, Iridium-Catalyzed Silylation of Aromatic C-H Bonds. Angew. Chem. Int. Ed. 2017, 56, 1092-1096.
22. Su, B.; Cai, C.; Deng, M.; Wang, Q.-M., Spatial Configuration and Three-Dimensional Conformation Directed Design, Synthesis, Antiviral Activity, and Structure–Activity Relationships of Phenanthroindolizidine Analogues. J. Agric. Food. Chem. 2016, 64, 2039-2045.
21. Su, B.; Cao, Z.-C.; Shi, Z.-J., Exploration of Earth-Abundant Transition Metals (Fe, Co, and Ni) as Catalysts in Unreactive Chemical Bond Activations. Acc. Chem. Res. 2015, 48, 886-896.
20. Su, B.; Wei, J.B.; Wu, W.L.; Shi, Z.-J., Diversity-Oriented Synthesis through Rh-Catalyzed Selective Transformations of a Novel Multirole Directing Group. ChemCatChem 2015, 7, 2986-2990.
19. Su, B.; Zhang, H.; Deng, M.; Wang, Q.-M., An enantioselective strategy for the total synthesis of (S)-tylophorine via catalytic asymmetric allylation and a one-pot DMAP-promoted isocyanate formation/Lewis acid catalyzed cyclization sequence. Org. Biomol. Chem. 2014, 12, 3616-3621.
18. Su, B.;1 Deng, M.;1 Wang, Q.-M., Sodium Nitrite-Catalyzed Aerobic Oxidative Csp2-Csp3 Coupling: Direct Construction of the 4-Aryldihydroisoquinolinone Moiety. Adv. Synth. & Catal. 2014, 356, 977-981. (1Equal contribution)
17. Su, B.;1 Cai, C. L.;1 Deng, M.; Liang, D. M.; Wang, L. Z.; Wang, Q.-M, Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives. Bioorg. Med. Chem. Lett. 2014, 24, 2881-2884. (1Equal contribution)
16. Su, B.;1 Chen, F.;1 Wang, L.; Wang, Q.-M., Design, Synthesis, Antiviral Activity, and Structure–Activity Relationships (SARs) of Two Types of Structurally Novel Phenanthroindo/quinolizidine Analogues. J. Agric. Food. Chem. 2014, 62, 1233-1239. (1Equal contribution)
15. Yang, M. Y.; Su, B.; Wang, Y.; Chen, K.; Jiang, X. Y.; Zhang, Y. F.; Zhang, X. S.; Chen, G. H.; Cheng, Y.; Cao, Z. C.; Guo, Q. Y.; Wang, L. S.; Shi, Z. -J., Silver-catalysed direct amination of unactivated C-H bonds of functionalized molecules. Nature Commun. 2014, 5. 4707-4712.
14. Su, B.;1 Deng, M.;1 Wang, Q.-M.,Bioinspired Construction of a Spirocyclohexadienone Moiety via Sodium Nitrite Catalyzed Aerobic Intramolecular Oxidative Phenol Coupling. Org. Lett. 2013, 15, 1606–1609. (1Equal contribution)
13. Su, B.;1 Chen, F. Z.;1 Wang, Q.-M., A Novel Strategy for the Synthesis of Phenanthroindolizidine alkaloids via one-pot Intramolecular Schmidt/ Bischler-Napieralski/ Imine-reduction reaction. J. Org. Chem. 2013, 78, 2775–2779. (1Equal contribution)
12. Su, B.; Deng, M.; Wang, Q.-M., The first enantioselective approach to 13a-methyl-14-hydroxyphen- anthroindolizidine alkaloids: synthetic studies towards hypoestestatin 2. Eur. J. Org. Chem. 2013, 10, 1979–1985.
11. Su, B.; Cai, C. L.; Wang, Q.-M., Enantioselective Approach to 13a-Methylphenanthroindolizidine Alkaloids. J. Org. Chem. 2012, 77, 7981–7987.
10. Su, B.; Li, L.; Hu, Y. N.; Liu, Y. X.; Wang, Q.-M., A Novel Sodium Nitrite-Catalyzed Oxidative Coupling for Constructing Polymethoxyphenanthrene Rings. Adv. Synth. Catal. 2012, 354, 383–387.
9. L Li, B Su, Y Liu, Q Wang An Unprecedented Cyano-Induced Sodium Nitrite-Catalyzed C (sp3)-H and C (sp2)-H Coupling Reaction Current Organic Synthesis 2018, 15, 989-994.
8. H Zhang, G Li, B Su, M Deng, YX Liu, YC Gu, QM Wang Total synthesis of the reported structure of 13a-hydroxytylophorine Scientific reports 2017, 7, 1-7.
7. Deng, M.; Su, B.; Zhang, H.; Liu, Y. X.; Wang, Q.-M., Total synthesis of phenanthroindolizidine alkaloids via asymmetric deprotonation of N-Boc-pyrrolidine. Rsc Adv. 2014, 4, 14979-14984.
6. Chen, F.; Su, B.; Wang, Q.-M., Asymmetric synthesis of (S)-tylophorine and (S)-cryptopleurine via one-pot Curtius rearrangement and Friedel-Crafts reaction tandem sequence. Org. Chem. Front. 2014, 1, 674-677.
5. Wu, M.; Li, L.; Su, B.; Liu, Z. H.; Wang, Q., First total synthesis of (+)-6-O-desmethylantofine. Org. Biomol. Chem. 2011, 9, 141-145.
4. Wu, M.; Li, L.; Feng, A. Z.; Su, B.; Liang, D. M.; Liu, Y. X.; Wang, Q.-M.,“First total synthesis of Papilistatin.” Org. Biomol. Chem. 2011, 9, 2539-2542.
3. Wang, K. L.; Su, B.; Wang, Z. W.; Wu, M.; Li, Z.; Hu, Y. N.; Fan, Z. J.; Mi, N.; Wang, Q.-M., Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives. J. Agric Food Chem. 2010, 58, 2703-2709.
2. Wang, K. L.; Hu, Y. N.; Wu, M.; Li, Z.; Liu, Z. H.; Su, B.; Yu, A.; Liu, Y.; Wang, Q.-M., “m-CPBA/TFA an efficient nonmetallic reagent for oxidative coupling of 1,2-diarylethylenes.” Tetrahedron. 2010, 66, 9135-9140.
1. Wang, K. L.; Hu, Y. N.; Li, Z.; Wu, M.; Liu, Z. H.; Su, B.; Yu, A.; Liu, Y.; Wang, Q.-M., A simple and efficient oxidative coupling of aromatic nuclei mediated by manganese dioxide. Synthesis. 2010, 7, 1083-1090.